Late Neurological Syndrome That Developed After Carbon Monoxide Intoxication a Case Report
DOI:
https://doi.org/10.17986/blm.2014191768Keywords:
carbon monoxide, neurology, forensic medicine, imagingAbstract
Carbon monoxide (CO) is a colorless, odorless, and non-irritant gas occurring as a product of incomplete combustion and it is lighter than air. Intoxication with this gas is usually seen during the winter months depending on unsuitable chimney stoves or heaters burned as charcoal in a closed environment. CO intoxication is a serious condition, it can result in death or severe neurological disorders. In rare cases of CO intoxication, after the short-term recovery period after acute treatment, late neurological syndrome may develop. In this syndrome, a variety of neurological and/or psychiatric symptoms accompanied by hyperintense lesions in the subcortical white matter especially in the basal ganglia in typical cranial computed tomography and magnetic resonance imaging (MRI) are observed. Prognosis of patients is closely associated with white matter lesions on brain MRI. In this study, the presence of periventricular hyperintensity on T2-weighted images in cranial MRI as late neurological syndrome sign that developed after carbon monoxide intoxication in a 65 year old female patient is presented. It is known that CO poisoning has serious harms in the acute period. In these cases it should be kept in mind that, as defined in our case, late neurological syndrome symptoms may occur after about a month from intoxication. Therefore, regular follow-up of patients should be performed and they need to be re-evaluated in terms of forensic reports.
Keywords: Carbon monoxide, neurology, forensic medicine, imaging.
Downloads
References
Şenoğlu N, Öksüz H, Zencirci B, Ezberci M, Tuncer D. Parkinsonism after carbonmonoxide intoxication: Case Report. J Neurol Sci 2005;22:41;292-6.
Sargın AE, Dönmez H, Örsel S, Yoldaş TK. Karbonmonoksit zehirlenmesine bağlı bir geç ensefalopati olgusunda nöropsikiyatrik bulgular. Nöropsikiyatri Arşivi 2009;46:121-4.
Yüksel EG, Taşkın O, Ovalı GY, Karaçam M, Danacı AE. Olgu Sunumu: karbonmonoksit zehirlenmesi sonrasında ortaya çıkan kleptomani ve diğer psikiyatrik belirtiler. Türk Psikiyatri Dergisi 2007:18:80-6.
Karayel F, Sav AM. Merkez sinir sistemi metabolik hastalıklarındaki patolojik bulguların adli tıp açısından önemi. Türk Ekopatoloji Dergisi 2004;10:35-8.
Durak D. Karbonmonoksit zehirlenmesine bağlı ölümler. Bursa Devlet Hast Bült 1999;15(2):131-3.
Azmak D, Çetin G, Kolusayın Ö, Soysal Z. Karbonmonoksit zehirlenmesine bağlı ölümler. Adli Tıp Dergisi 1994;10:73-81.
Berber G, Üzün İ, Ak N. 1995-1998 yılları arasında ATK Morg İhtisas Dairesi’ne gelen karbonmonoksit zehirlenmelerinin değerlendirilmesi. Yıllık Adli Tıp Toplantıları Kitabı, 2002;(16-19 Mayıs 2002 Antalya):222-7.
Türkmen N, Akgöz S. Bursa’da otopsisi yapılan karbonmonoksit zehirlenmesine bağlı ölümler. Adli Tıp Dergisi 2005;19(2):20-5.
Cantürk N, Başbulut AZ, Cantürk G, Dağalp R. Ankara'da 2002-2006 yılları arasında karbonmonoksit zehirlenmeleri otopsi olgularının değerlendirilmesi. Adli Tıp Dergisi 2008;22(1):25-30.
Turan AA, Pakiş I, Arıcan N, Karayel F, Şam B, Kavas G, Öz B. Karbonmonoksit zehirlenmeleri sonrası geç dönem nöropatolojik değişiklikler: İki olgu sunumu. Adli Tıp Bülteni 2003;8(2):53-7. DOI: https://doi.org/10.17986/blm.200382498
Chang KH, Han MH, Kim HS, Wie BA, Han MC. Delayed encephalopathy after acute carbon monoxide intoxication: MR imaging features and distribution of cerebral white matter lesions. Radiology 1992;184(1):117-22. DOI: https://doi.org/10.1148/radiology.184.1.1609067
Horowitz AL, Kaplan R, Sarpel G. Carbon monoxide toxicity: MR imaging in the brain. Radiology. 1987 Mar;162(3):787-8. DOI: https://doi.org/10.1148/radiology.162.3.3809495
Aydın H, Akın M, Boyraz E, Çolakkaya M. Karbonmonoksit intoksikasyonuna bağlı geç tip ensefalopati. J Clin Anal Med 2011;2(1):34-6.
Silver DAT, Cross M, Fox B, Paxton RM. Computed tomography of the brain in acute carbon monoxide poisoning. Clin Radiol 1996; 51:480-3. DOI: https://doi.org/10.1016/S0009-9260(96)80186-3
Uchino A, Hasuo K, Shida K, Matsumoto S, Yasumori K, Masuda K. MRI of the brain in chronic carbon monoxide poisoning. Neuroradiology 1994; 36:399-401. DOI: https://doi.org/10.1007/BF00612127
Hanoğlu L, Yalçıner B, Özer F, Tüzün M, Altıntaş H, Arpacı B. Karbonmonoksit entoksikasyonunda geç dönem nörolojik bozukluklar. Düşünen Adam 1991;4(3):79-81.
Downloads
Published
Issue
Section
License
The Journal and content of this website is licensed under the terms of the Creative Commons Attribution (CC BY) License. The Creative Commons Attribution License (CC BY) allows users to copy, distribute and transmit an article, adapt the article and make commercial use of the article. The CC BY license permits commercial and non-commercial re-use of an open access article, as long as the author is properly attributed.