Cooccurence of Volatile Substance Positivity and Ischaemic Cardiac Disease Case Report

Authors

  • Gökhan Ersoy İstanbul Üniversitesi Adli Tıp Enstitüsü
  • Murat Nihat Arslan Adli Tıp Kurumu Başkanlığı Morg İhtisas Dairesi
  • Işıl Pakiş Adli Tıp Kurumu Başkanlığı Morg İhtisas Dairesi
  • İbrahim Üzün Adli Tıp Kurumu Başkanlığı

DOI:

https://doi.org/10.17986/blm.2009141688

Keywords:

forensic pathology, toxicology, autopsy, arrhythmia, coronary disease

Abstract

Volatile substance abuse is a major problem, especially in teens. It is a popular recreational activity among young population. Beside this, there is a group, which uses the substances for 10-20 years. Case is 37 years old man without volatile substances history from his parent. It was very easy to smell an odor like “industrial thinner” during the autopsy. There were an obvious ischemic cardiac disease and toxicologic screening was corrected the suspects about volatile substances occurrence. Cardiac toxicity is the leading cause for the death attributing the volatile substances. They may cause ventricular fibrillation or other rhythm disturbances and coronary vasospasm. Therefore, it may create a synergic effect to use a volatile on the ground of ischemic cardiac disease. It would be easier to decide to cause of death if medical examiner obtain sufficient medical and legal history. Toxicologic screening must be done separately for blood, urine, lung, brain and kidney and reports must show quantitative results if possible.

Key words: Forensic Pathology, toxicology, autopsy, arrhythmia, coronary disease

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References

Öztek Z, Akdur R, Ayçan S, Afşar OZ, Soydal T, Üner S, Bal E, Demirören M, Altınyollar H, Evci D. “Herkese sağlık”: Türkiye’nin hedef ve Stratejileri (Sağlık 21). İnci baskı. Ankara: T.C. Sağlık Bakanlığı, 2001: 31

Wick R, Gilbert JD, Felgate P, Byard RW. Inhalant deaths in South Australia: a 20-year retrospective autopsy study. Am J Forensic Med Pathol 2007; 28(4):319-22. DOI: https://doi.org/10.1097/PAF.0b013e31815b48b0

Anderson HR, Macnair RS, Ramsey JD. Deaths from abuse of volatile substances: a national epidemiological study. Br Med J (Clin Res Ed) 1985; 290(64):304-7. DOI: https://doi.org/10.1136/bmj.290.6464.304

Maxwell JC. Deaths related to the inhalation of volatile substances in Texas: 1988-1998. Am J Drug Alcohol Abuse 2001;27(4):689-97. (Abstract) DOI: https://doi.org/10.1081/ADA-100107662

Spiller HA. Epidemiology of volatile substance abuse (VSA) cases reported to US poison centers. Am J Drug Alcohol Abuse 2004;30(1): 155-65. (Abstract) DOI: https://doi.org/10.1081/ADA-120029871

Vural M, Dayi ŞÜ, Tartan Z, Kaşıkçıoğlu H, Ök- men E, Çam N. Tiner maruziyeti sonucu gelişen miyokard infarktüsü olgusu. Anadolu Kardiyol Derg 2003;3: 363-5.

Meadows R, Verghese A. Medical complications of glue sniffing. South Med J 1996;89(5):455-62. DOI: https://doi.org/10.1097/00007611-199605000-00001

Adgey AA, Johnston PW, McMechan S. Sudden cardiac death and substance abuse. Resuscitation 1995;29(3):219-21. DOI: https://doi.org/10.1016/0300-9572(95)00854-M

Al-Alousi LM. Pathology of volatile substance abuse: a case report and a literature review. Med Sei Law. 1989;29(3):189-208. DOI: https://doi.org/10.1177/002580248902900304

Byard RW, Gilbert JD, Terlet J. Death associated with volatile substance inhalation-Histologic, scanning electron microscopic and energy dispersive X- ray spectral analyses of lung tissue. Forensic Sei Int 2006; 171 (2-3): 118-21. DOI: https://doi.org/10.1016/j.forsciint.2006.10.008

Kurtzman TL, Otsuka KN and Wahl RA. Inhalant abuse by adolescents. J Adolesc Health 2001;28: 170-80.

Wille SMR, Lambert WEE. Volatile substance abuse postmortem diagnosis. Forensic Sei Int 2004;142: 135-56. DOI: https://doi.org/10.1016/j.forsciint.2004.02.015

Alpay N, Ulaşoğlu C, Karamustafalıoğlu N. Uçucu madde kullananlarda karaciğer histopatolojisi. Düşünen Adam Dergisi 1996;9(4):15-17

Crowe AV, Howse M, Bell GM, Henry JA. Substance abuse and the kidney. QJM 2000;93(3):147-52. DOI: https://doi.org/10.1093/qjmed/93.3.147

www.drugabuse.gov/Infofacts/inhalants.html Erişim tarihi: 4/5/2007

Ogel G, Tamar D, Evren C, Çakmak D. İstanbul’da lise gençleri arasında sigara, alkol ve madde kullanım yaygınlığı. Klinik psikiyatri 2000;3:242-5.

S. Karadayi, M. Acikkol, S. Cengiz The Profile of Volatile Substance Abuser in Alcohol and Substance Treatment Centre in Istanbul. Proceeding of the American Academy of Forensic Sciences 2006;12: 349.

M. Statheropoulos, C. Spiliopoulou, A. Agapiou A study of volatile organic compounds evolved from the decaying human body. Forensic Sei Int 2005; 153(2-3): 147-155. DOI: https://doi.org/10.1016/j.forsciint.2004.08.015

Yajima Y, Funayama M, Niitsu H, Nata M, Kana- waku Y, Sakai J, Aoki Y. Concentrations of toluene in the body killed by an injury to the head shortly after ingesting thinner. Forensic Sei Int 2005; 147(1) :9-12. DOI: https://doi.org/10.1016/j.forsciint.2004.03.036

Anderson HR, Dick B, Macnair RS, Palmer JC, Ramsey JD. An investigation of 140 deaths associated with volatile substance abuse in the United Kingdom (1971-1981). Hum Toxicol 1982;1(3):207- 221. DOI: https://doi.org/10.1177/096032718200100303

Shepherd RT. Mechanism of sudden death associated volatile substance abuse. Human Toxicol 1989; 8:287-92. DOI: https://doi.org/10.1177/096032718900800406

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Published

2009-04-01

Issue

Section

Case Report

How to Cite

1.
Ersoy G, Arslan MN, Pakiş I, Üzün İbrahim. Cooccurence of Volatile Substance Positivity and Ischaemic Cardiac Disease Case Report. Bull Leg Med. 2009;14(1):34-39. https://doi.org/10.17986/blm.2009141688