Sudden Unexpected Death in Epileptic Patient Case Report

Authors

  • Erdal Özer Çorum Adli Tıp Şube Müdürlüğü
  • Talat Yurtman Adli Tıp Kurumu Ankara Grup Başkanlığı
  • Celal Bütün Cumhuriyet Üniversitesi Tıp Fakültesi Adli Tıp Anabilim Dalı

DOI:

https://doi.org/10.17986/blm.2006112610

Keywords:

epilepsy, sudden death, sudep, pregnancy

Abstract

The probability of sudden death for patient with epilepsy is almost 24 times higher than for someone without epilepsy. Our case was a 40 years old woman with epilepsy who was six months pregnant when she was dead at her home. Although external examination and autopsy were performed, no pathological signs indicating a cause for death or no signs of trauma indicating an epileptic seizure were observed. Nothing was found in toxicological analysis to reveal a reason for death. When external examination, autopsy report, scene investigation and medical history in forensic investigation folder are evaluated together, reason of death is thought to be definete sudden unexpected death in epileptic patient according to SU-DEP criteria. This case is presented to attract attention to autopsies of patients with epilepsy and to discuss the principles of medicolegal approach to these cases.

Key words: Epilepsy, sudden death, SUDEP, pregnancy

Downloads

Download data is not yet available.

References

Leestma JE, Annegers JF, Brodie MJ, Brown S, Schraedser, Siscovick D, Wannamaker BB, Tennis PS, Cierpial MA and Earl NL. Sudden unexplained death in epilepsy: observations from a large clinical development program. Epilepsia 1997;38:47-55. DOI: https://doi.org/10.1111/j.1528-1157.1997.tb01076.x

http://www.itfnoroloji.org/epilepsi/Epilepsi.html Erişim:21.6.2005

Hauser WA, Hesdorfer DC. Mortality. In: Epilepsy: frequency, causes and consequences. MD Epilepsy Foundation of USA, 1990:269-326.

Nashef L and Brown S. Epilepsy and sudden death. Lancet 1996;348:1324-25. DOI: https://doi.org/10.1016/S0140-6736(05)65402-5

Nashef L. Sudden unexpected death in epilepsy: Terminology and definitions. Epilepsia 1997;38(Suppl ll):6-8. DOI: https://doi.org/10.1111/j.1528-1157.1997.tb06130.x

http://www.emedicine.com. Erişim: 2005-06-28

Appleton RE. Sudden, unexpected death in epilepsy in children. Seizure 1997;6:175-77. DOI: https://doi.org/10.1016/S1059-1311(97)80002-7

Leestma JE et al. Sudden and unexpected deaths associated with seizures : Analysis of 66 cases. Epilepsia 1984;25:84-88.

Nei M et al. EKG abnormalities during partial seizures in refractory epilepsy. Epilepsia 2000;41:542-48. DOI: https://doi.org/10.1111/j.1528-1157.2000.tb00207.x

Opeskin K et al Sudden and unexpected death in epilepsy in Victoria. J Clin Neurosci 2000;7(l):34-7 DOI: https://doi.org/10.1054/jocn.1999.0137

Leestma JE et al. Sudden and unexpected deaths associated with seizures : Analysis of 66 cases. Epilepsia 1984;25:84-88. DOI: https://doi.org/10.1111/j.1528-1157.1984.tb04159.x

Earnest MP et al. The sudden and unexplained death syndrome in epilepsy : Demographic, clinical and post mortem features. Epilepsia 1992;33:310-16. DOI: https://doi.org/10.1111/j.1528-1157.1992.tb02321.x

Thom M. Pathological findings in SUDEP. CEPR 2001;408-14. DOI: https://doi.org/10.1023/A:1013258200829

Ficker DM. Sudden unexplained death and injury in epilepsy. Epilepsia 2000;41(Suppl 2):7-12. DOI: https://doi.org/10.1111/j.1528-1157.2000.tb01519.x

Thom M. Neuropathologie findings in postmortem studies of sudden death in epilepsy. Epilepsia 1997;38(Suppl ll):32-34. DOI: https://doi.org/10.1111/j.1528-1157.1997.tb06123.x

Di Maio JMV, Di Maio JD. Forensic Pathology. CRC Press, Florida. 1993:43-83. DOI: https://doi.org/10.1007/BF02844819

Leestma JE et al. A prospective study on sudden and unexpected death in epilepsy. Ann Neurol 1989;26:195-203. DOI: https://doi.org/10.1002/ana.410260203

Dashieff RM et al. Sudden unexpected death of epileptic patients due to cardiac arythmia after seizure. Arch Neurol 1986;43:194-96. DOI: https://doi.org/10.1001/archneur.1986.00520020080028

George JR et al. Comparison of anti-epileptic drug levels in different cases of sudden death. J Forensic Sei 1998;43:598-603. DOI: https://doi.org/10.1520/JFS16186J

Opeskin K et al. Comparison of anti-epileptic drug levels in sudden unexpected deaths in epilepsy with deaths from other causes. Epilepsia 1999;40:1795-98. DOI: https://doi.org/10.1111/j.1528-1157.1999.tb01600.x

Waljzak TS, Leppik IE, D'amelio M et al. Incidence and risk factors in sudden unexpected death in epilepsy: A prospective cohort study. Neurology 2001;56(4):519-25. DOI: https://doi.org/10.1212/WNL.56.4.519

Downloads

Published

2006-08-01

Issue

Section

Case Report

How to Cite

1.
Özer E, Yurtman T, Bütün C. Sudden Unexpected Death in Epileptic Patient Case Report. Bull Leg Med. 2006;11(2):71-74. https://doi.org/10.17986/blm.2006112610