Ani Bebek Ölümü Sendromu

Yazarlar

  • Ümit Ünüvar Atılmış Adli Tıp Kurumu Başkanlığı
  • Halis Dokgöz Mersin Üniversitesi Tıp Fakültesi Adli Tıp Anabilim Dalı
  • Ali Yemişçigil Ege Üniversitesi Tıp Fakültesi Adli Tıp Anabilim Dalı

DOI:

https://doi.org/10.17986/blm.2006111603

Anahtar Kelimeler:

ani bebek ölümü sendromu- bebek- risk faktörleri- uyku- otopsi

Öz

Bir yaşın altındaki bebeklerin ani ye beklenmedik ölümlerinde; tıbbi ve sosyal öykü, olay yeri incelemesi, yapılan otopsi ve tetkiklere karşın ölüm sebebi açıklanamayan ölümler ani bebek ölümü sendromu (ABÖS) olarak tanımlanmaktadır. Gelişmiş ülkelerde yenidoğan döneminden sonra çocukluk çağında mortalitenin önemli nedenlerinden biridir. Bebekler genellikle uyku esnasında ölü bulunur ve ölüme neden olacak herhangi bir bulgu yoktur. Bugüne kadar birçok çalışma yapılmasına karşın sorumlu mekanizmalar ve fizyopatoloji henüz aydınlatı-lamamış, ancak riski artıran birçok etken tanımlanmıştır. Çalışmada; ABOS güncel literatür ışığında değerlendirilmiş, risk etkenleri gözden geçirilmiş, sıklığının azaltılmasına yönelik önlemler belirtilmiş, otopsinin yanı sıra öykünün önemi de vurgulanmıştır.

Anahtar kelimeler: Ani bebek ölümü sendromu, bebek, risk faktörleri, uyku, otopsi.

İndirmeler

İndirme verisi henüz mevcut değil.

Kaynaklar

Committee on Child Abuse and Neglect. American Academy of Pediatrics: distinguishing sudden infant death syndrome from child abuse fatalities. Pediatrics 2001; 107:437. DOI: https://doi.org/10.1542/peds.107.2.437

Editorial note. Sudden Infant Death Syndrome - United States, 1983-1994. MMWR 1996; 45(40):859-63.

Willinger M, James LS, Catz C. Defining the sudden infant death syndrome (SIDS): deliberations of an expert panel convened by the National Institute of Child Health and Human Development. Pediatr Pathol 1991; 11:677-684. DOI: https://doi.org/10.3109/15513819109065465

Beckwith JB. Discussion of terminology and definition of sudden infant death syndrome. In: Bergman AB, Beckwith JB, Ray CG, eds. Sudden Infant Death Syndrome: Proceedings of the Second International Conference on Causes of Sudden Death in Infants. Seattle, WA: University of Washington Press; 1970:14-22.

Krous H, Beckwith JB, Byard RW, Rognum TO, Ba- janowski EAM et al. Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach. Pediatrics 2004; 114:234-238. DOI: https://doi.org/10.1542/peds.114.1.234

Opdal SH, Rognum TO. The sudden infant death syndrome gene: does it exist? Pediatrics 2004; 114: 506-512. DOI: https://doi.org/10.1542/peds.2004-0683

Leach CEA, Blair PS, Fleming PJ, Smith IJ et al. The CESDI SUDI Research Group Epidemiology of SIDS and explained sudden infant deaths. Pediatrics 1999; 104:43-52. DOI: https://doi.org/10.1542/peds.104.4.e43

Kijima K, Sasaki A, Niki A, Umetsu K, Osawa M, Matoba R, Hatasaka K. Sudden infant death syndrome is not associated with the mutation of PHOX2B gene, a major causative gene of congenital central hypoventilation syndrome. Tohoku J Exp Med 2004; 203:65-68. DOI: https://doi.org/10.1620/tjem.203.65

De-Kun Li, Willinger M, Petitti D, Odouli R, Liu L, Hoffman HJ. Use of a dummy (pacifier) during sleep and risk of sudden infant death syndrome (SIDS): population based case-control study. BMJ 2006; 332: 18-22. DOI: https://doi.org/10.1136/bmj.38671.640475.55

Ponsonby AL, Dwyer T, Couper D. Sleeping position, infant apnea, and cyanosis: A population-based study. Pediatrics 1997; 99:3-9. DOI: https://doi.org/10.1542/peds.99.1.e3

Unger B, Kemp JS, Wilkins D et al. Racial disparity and modifiable risk factors among infants dying suddenly and unexpectedly. Pediatrics 2003; 111:127. DOI: https://doi.org/10.1542/peds.111.2.e127

Meadow R. Unnatural sudden infant death. Arch Dis Child 1999; 80:7-14. DOI: https://doi.org/10.1136/adc.80.1.7

Limerick SR, Bacon CJ. Terminology used by pathologists in reporting on sudden infant deaths. J Clin Pathol 2004; 57:309-311. DOI: https://doi.org/10.1136/jcp.2003.013052

International Statistical Classification of Diseases and Related Health Problems 10th Revision Version for 2003. http://www3.who.int/icd/vollhtm2003/fr-icd.htm. Erişim: 27.03.2006.

Jones KL, Krous HF, Nadeau J, Blackbourne B, Zi- elke HR, Gozal D. Vascular endothelial growth factor in the cerebrospinal fluid of infants who died of sudden infant death syndrome: evidence for antecedent hypoxia. Pediatrics 2003; 111: 358. DOI: https://doi.org/10.1542/peds.111.2.358

Moon RY, Patel KM, Shaefer SJM. Sudden infant death syndrome in child care settings. Pediatrics 2000; 106: 295. DOI: https://doi.org/10.1542/peds.106.2.295

Carroll-Pankhurst C, Mortimer JEA. Sudden infant death syndrome, bedsharing, parental weight, and age at death. Pediatrics 2001; 107:530. DOI: https://doi.org/10.1542/peds.107.3.530

Gökçe S, Baysal SU. Ani bebek ölümü sendromu. İst Tıp Fak Mecmuası 2004; 7:1-7.

Beckwith JB. The sudden infant death syndrome. Curr Probl Pediatr 1973; 3:1-36. (Abstract) DOI: https://doi.org/10.1016/S0045-9380(73)80020-9

Mooney JA, Helms PJ, Jolliffe IT. Higher incidence of SIDS at weekends, especially in younger infants. Arch Dis Child 2004; 89:670-672. DOI: https://doi.org/10.1136/adc.2002.023408

Scheers-Masters JR, Schootman M, Thach BT. Heat stress and sudden infant death syndrome incidence: a United States population epidemiologic study. Pediatrics 2004; 113:586-592. DOI: https://doi.org/10.1542/peds.113.6.e586

Mage DT. Seasonal variation of sudden infant death syndrome in Hawaii. J Epidemiol Community Health 2004; 58:912-916. DOI: https://doi.org/10.1136/jech.2003.018176

Kochanek KD, Hudson BL. Advance report of final mortality statistics, 1992. Mon Vital Stat Rep 1995; 43:10-12.

Arias E, MacDorman MF, Strobino DM, Guyer B. Annual summary of vital statistics-2002. Pediatrics 2003; 112:1215-1230. DOI: https://doi.org/10.1542/peds.112.6.1215

Southall DP, Plunkett MCB, Banks MW, Falkov AF et al. Covert video recordings of life-threatening child abuse: lessons for child protection. Pediatrics 1997; 100:735-760. DOI: https://doi.org/10.1542/peds.100.5.735

Jonge GA, Lanting Cl, Brand R, Ruys JH, Sem- mekrot BA, Wouwe JP. Sudden infant death syndrome in child care settings in the Netherlands. Arch Dis Child 2004; 89:427-430. DOI: https://doi.org/10.1136/adc.2003.029884

Bubnaitiene V, Kalodieno R, Kövalas R. Case-control study of sudden infant death syndrome in Lithuania, 1997-2000. BMC Pediatrics 2005; 5:41-49. DOI: https://doi.org/10.1186/1471-2431-5-41

Guntheroth WG, Spiers PS. Thermal stress in sudden infant death: is there an ambiguity with the rebreathing hypothesis? Pediatrics 2001; 107: 693. DOI: https://doi.org/10.1542/peds.107.4.693

Wailoo M, Ball H, Fleming P, Platt MW. Infants bed-sharing with mothers. Arch Dis Child 2004; 89:1082-1083. DOI: https://doi.org/10.1136/adc.2004.054312

Horne RSC, Ferens D, Watts AM, Vitkovic J, Lacey B, Andrew S et al. Effects of maternal tobacco smoking, sleeping position, and sleep state on arousal in healthy term infants. Arch Dis Child Fetal Neonatal Ed 2002; 87:100-105. DOI: https://doi.org/10.1136/fn.87.2.F100

McKenna JJ, McDade T. Why babies should never sleep alone: A review of the co-sleeping controversy in relation to SIDS, bedsharing and breast feeding. Pediatric Res Rev 2005; 6:134-152. DOI: https://doi.org/10.1016/j.prrv.2005.03.006

Blair PS, Sidebotham P, Berry PJ, Evans M, Fleming PJ. Major epidemiological changes in sudden infant death syndrome: a 20-year population-based study in the UK. Lancet 2006; 367:314-19. DOI: https://doi.org/10.1016/S0140-6736(06)67968-3

Matturri L, Ottaviani G, Lavezzi AM. Sudden infant death triggered by dive reflex. J Clin Pathol 2005; 58:77-80. DOI: https://doi.org/10.1136/jcp.2004.020867

Guntheroth WG, Spiers PS. The triple risk hypotheses in sudden infant death syndrome. Pediatrics 2002; 110:64-70. DOI: https://doi.org/10.1542/peds.110.5.e64

Vennelle M, Brander PE, Kingshott RN, Rees K et al. Is there a familial association between obstructive sleep apnoea/hypopnoea and the sudden infant death syndrome? Thorax 2004; 59:337-341. DOI: https://doi.org/10.1136/thx.2003.006783

Gessner BD, Ives GC, Perham-Hester KA. Association between sudden infant death syndrome and prone sleep position, bed sharing, and sleeping outside an infant crib in Alaska. Pediatrics 2001; 108:923. DOI: https://doi.org/10.1542/peds.108.4.923

Matthews T, McDonnell M, McGarvey C, Loftus G, O’Regan MA. Multivariate “time based” analysis of SIDS risk factors. Arch Dis Child 2004; 89:267-271. DOI: https://doi.org/10.1136/adc.2002.025486

Bauchner H, Zuckerman B, McClain M et al. Risk of sudden infant death syndrome among infants with inutero exposure to cocaine. J Pediatr 1988; 113:831-834. (Abstract) DOI: https://doi.org/10.1016/S0022-3476(88)80009-X

Davidson-Ward SL, Bautista D, Chan L et al. Sudden infant death syndrome in infants of substance abusing mothers. J Pediatr 1990; 117:876-881. (Abstract) DOI: https://doi.org/10.1016/S0022-3476(05)80125-8

Anderson ME, Johnson DC, Batal HA. Sudden infant death syndrome and prenatal maternal smoking: rising attributed risk in the back to sleep era. BMC Medicine 2005; 3:4-11. DOI: https://doi.org/10.1186/1741-7015-3-4

Reid GM. Sudden infant death syndrome (SIDS): microgravity and inadequate sensory stimulation. Medical Hypotheses 2006; 66:920-924. DOI: https://doi.org/10.1016/j.mehy.2005.10.027

Smith GCS, Wood AM, Pell JP, Dobbie R. Sudden infant death syndrome and complications in other pregnancies. Lancet 2005; 366:2107-2111. DOI: https://doi.org/10.1016/S0140-6736(05)67888-9

Nelson EAS, Schiefenhoevel W, Haimerl F. Child care practices in nonindustrialized societies. Pediatrics 2000; 105:75-80. DOI: https://doi.org/10.1542/peds.105.6.e75

Heininger U, Kleemann WJ, Cherry JD and Sudden Infant Death Syndrome Study Group. A controlled study of the relationship between bordetel- la pertussis infections and sudden unexpected deaths among German infants. Pediatrics 2004; 114:9-15. DOI: https://doi.org/10.1542/peds.114.1.e9

Nevas M, Lindstrom M, Virtanen A, Hielm S, Kuusi M. et al. Infant botulism acquired from household dust presenting as sudden infant death syndrome. J Clin Microbiol 2005; 43:511-513. DOI: https://doi.org/10.1128/JCM.43.1.511-513.2005

Dales R, Burnett RT, Smith-Doiron M, Stieb DM, Brook JR. Air pollution and sudden infant death syndrome. Pediatrics 2004; 113:628-631. DOI: https://doi.org/10.1542/peds.113.6.e628

Hunt CE. Gene-environment interactions: implications for sudden unexpected deaths in infancy. Arch Dis Child 2005; 90:48-53. DOI: https://doi.org/10.1136/adc.2004.051458

Arıcan N, Fincancı ŞK, Sözen Ş, İnce H. Ani çocuk ölümü sendromunda otopsi bulguları: bir olgu sunumu. I. Adli Bilimler Kongresi Kitapçığı, Adana, 1994; 312-313.

İnanıcı MA, Yorulmaz C, Cantürk N. Bir olgu nedeniyle ani bebek ölümü sendromu. Adli Tıp Bülteni 2001;6:130-133. DOI: https://doi.org/10.17986/blm.200163464

Yukawa N, Carter N, Rutty G, Green MA. Intraalveolar haemorrhage in sudden infant death syndrome: a cause for concern? J Clin Pathol 1999; 52:581-587. DOI: https://doi.org/10.1136/jcp.52.8.581

Hunt CE. Genes and sudden infant death syndrome. Pediatric Res 2004; 56:391. DOI: https://doi.org/10.1203/01.PDR.0000135999.55443.8B

Matturri L, Ottaviani G, Benedetti G, Agosta E, Lavezzi AM. Unexpected perinatal death and sudden infant death syndrome (SIDS) anatomopathologie and legal aspects. Am J Forensic Med Pathol 2005; 26: 155-160. DOI: https://doi.org/10.1097/01.paf.0000163827.01339.b4

Weese-Mayer DE, Berry-Kravis EM, Zhou L, Maher BS et al. Sudden infant death syndrome: case- control frequency differences at genes pertinent to early autonomic nervous system embryologie development. Pediatric Res 2004; 56:392-395. DOI: https://doi.org/10.1203/01.PDR.0000136285.91048.4A

Dettmeyer R, Baasner A, Schlamann M, Padosch SA et al. Role of virus-induced myocardial affections in sudden infant death syndrome: a prospective postmortem study. Pediatric Res 2004; 55: 947-952. DOI: https://doi.org/10.1203/01.pdr.0000127022.45831.54

Hunt CE. Sudden Infant Death Syndrome. In: Behrman RE, Kliegman RM, Jenson HB (eds). Nelson Textbook of Pediatrics. 16th ed. W.B. Saunders Co, Philadelphia: 2000:2139.

Gislason T, Johannsson JH, Haraldsson A, Olafs- dottir BR, Jonsdottir H et al. Familial predisposition and cosegregation analysis of adult obstructive sleep apnea and the sudden infant death syndrome. Am J Respir Crit Care Med 2002; 166:833-838. DOI: https://doi.org/10.1164/rccm.2107121

Neff RA, Simmens SJ, Evans C, Mendelowitz D. Prenatal nicotine exposure alters central cardiorespiratory responses to hypoxia in rats: implications for sudden infant death syndrome. J Neurosci 2004; 24:9261-9268. DOI: https://doi.org/10.1523/JNEUROSCI.1918-04.2004

Wedekind H, Smits JPP, Schulze-Bahr E, Arnold R et al. De Novo mutation in the SCN5A gene associated with early onset of sudden infant death. Circulation 2001; 104:1158-1164. DOI: https://doi.org/10.1161/hc3501.095361

Emery MJ, Krous HF, Nadeau-Manning JM, Marek BT, Matsumoto AM. Serum testosterone and estradiol in sudden infant death. J Pediatr 2005; 147:586-591. DOI: https://doi.org/10.1016/j.jpeds.2005.05.011

Schwartz PJ. Stillbirths, sudden infant deaths, and long-QT syndrome: puzzle or mosaic, the pieces of the jigsaw are being fitted together. Circulation 2004; 109:2930-2932. DOI: https://doi.org/10.1161/01.CIR.0000133180.77213.43

Sawaguchia T, Katob I, Francoc P, Sottiauxc M, Kadhimc H, Shimizud S et al. Apnea, glial apoptosis and neuronal plasticity in the arousal pathway of victims of SIDS. Forensic Sei Int. 2005; 149:205-217. DOI: https://doi.org/10.1016/j.forsciint.2004.10.015

Craft AW, Hall DMB. Munchausen syndrome by proxy and sudden infant death. BMJ 2004; 328:1309-1312. DOI: https://doi.org/10.1136/bmj.328.7451.1309

Matthews T. Sudden unexpected infant death: infanticide or SIDS? Lancet 2005; 365:29-30. DOI: https://doi.org/10.1016/S0140-6736(04)17673-3

İndir

Yayınlanmış

2006-04-01

Sayı

Bölüm

Derleme

Nasıl Atıf Yapılır

1.
Atılmış Ümit Ünüvar, Dokgöz H, Yemişçigil A. Ani Bebek Ölümü Sendromu. Bull Leg Med. 2006;11(1):30-39. https://doi.org/10.17986/blm.2006111603