Adli Bilimlerde Aptamer Uygulamaları: Kokain Algılama ve Parmak İzi Belirleme Örneği

Yazarlar

  • Mustafa Oğuzhan Çağlayan Cumhuriyet Üniversitesi Nanoteknoloji Mühendisliği Bölümü, Sivas

DOI:

https://doi.org/10.17986/blm.2018136899

Anahtar Kelimeler:

aptamerler- adli bilim uygulamaları- biyosensörler- kokain tayini- gizli parmak izi

Öz

Yapay antikorlar olarak da bilinen aptamerler, farklı boyutlardaki hedef moleküllere, yüksek ilgi ve seçicilik ile bağlanan ve geçtiğimiz 30 yıl içerisinde çok farklı sensör uygulamalarında başarıyla kullanılan yakalama elemanlarıdır. Aptamerlerin bir organizmada üretilen antikorlar yerine laboratuvar ortamında üretilebilmesi, çoğaltılma ve saflaştırma aşamasının kolay olması ve sonsuz konfigürasyonda üretilebiliyor olması gibi eşsiz avantajları vardır. Askeri, çevresel, gıda güvenliği ve tıbbi uygulamalarının yanı sıra, adli bilimlerde de aptamerlerin kullanılması kaçınılmazdır. Bu makalede, aptamerlerin adli bilimlerde uygulamalarına yönelik örnekler verilmiştir. Literatürde, çok sayıda uygulama olması nedeniyle bu makalede, adli bilim ve adli tıpta sensörler için kokain ve adli bilim için parmak izi belirlemesi uygulamaları örnek olarak verilmiştir.

İndirmeler

İndirme verisi henüz mevcut değil.

Kaynaklar

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Yayınlanmış

2018-04-05

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Nasıl Atıf Yapılır

1.
Çağlayan MO. Adli Bilimlerde Aptamer Uygulamaları: Kokain Algılama ve Parmak İzi Belirleme Örneği. Bull Leg Med. 2018;23(1):53-59. https://doi.org/10.17986/blm.2018136899